Clinical Operations Manager, Prague, Czech Republic

This job is OPEN to APPLY for ALL Nationalities, unless otherwise specified.

We need a Clinical Operations Manager,

Clinical Operations Manager

Category: Clinical Development
Location: Prague, Czech Republic, CZ
Lead and develop a high performing clinical operations team that delivers quality, compliant and efficient execution across our global trial portfolio.

Your new role
As Clinical Operations Manager (COM) you will provide strategic oversight and line management for clinical operations staff, ensuring operational excellence across clinical trial execution. You will drive team performance, resource planning and professional development while partnering with cross functional stakeholders to deliver trials on time, on quality and in compliance with regulatory and company standards.

Day to day your tasks will include:

  • Provide line management, mentorship and development for clinical operations staff (CRAs), including performance reviews and individual development plans.
  • Define, monitor and report performance and productivity metrics (e.g., site visits, milestone completion, data quality) and lead initiatives to improve operational efficiency.
  • Collaborate with trial squads, Global Project Teams and cross functional partners within local team to align on resourcing, study priorities, timelines and operational execution.
  • Conduct accompanied site visits and quality checks with CRAs, embed RBQM principles, and ensure monitoring activities meet ICH GCP, regulatory and internal SOP requirements.
  • Oversee preparation for site audits and inspections, support resolution of serious breaches or data incidents, and maintain continuous inspection readiness.
  • Promote a culture of accountability, collaboration and continuous learning to support high quality in trial conduct and team performance.

Your new department
You will be part of the NN CRA Unit within CDC CZ and work closely with Trial Operations EUCAN, Global Trial Portfolio teams, Medical & Regulatory colleagues and key cross functional partners within CDC Czech Republic. Your role supports a global trial portfolio with local execution responsibility in the Czech Republic.

Your skills & qualifications

To succeed in this role, you should:

  • Hold a Master’s degree in life sciences or a related field.
  • Have 4+ years’ experience in clinical trial monitoring and 2+ years’ experience in people management within the pharmaceutical industry or a CRO, including co-monitoring, mentoring, performance evaluation, and team development
  • Strong leadership skills with the ability to motivate and develop teams, displaying resilience and adaptability under pressure.
  • Demonstrate excellent planning, prioritisation and organisational capabilities to manage multiple clinical trials, CRAs and timelines simultaneously, with a strategic mindset for resource management and audit/inspection readiness.
  • Have thorough knowledge of ICH GCP, clinical trial methodology and internal SOPs, with experience ensuring regulatory compliance and highquality execution.
  • Be experienced in applying Risk Based Quality Management (RBQM) principles, conducting quality checks and preparing for audits/inspections.
  • Possess excellent communication and stakeholder management skills, analytical thinking, and the ability to lead teams through change and ambiguity.

Working at Novo Nordisk
Every day we seek solutions that defeat serious chronic diseases. We combine scientific curiosity, warmth and determination to deliver long term improvements in patient health. At Novo Nordisk you will join a culture that values development, collaboration and accountability, and offers opportunities to grow professionally across global programmes.

Deadline
21st January 2026. (Applications are reviewed on an ongoing basis)

Novo Nordisk is not a typical healthcare company. In a modern world of quick fixes, we focus on solutions to defeat serious chronic diseases and promote long term health. Our unordinary mindset is at the heart of everything we do. We seek out new ideas and put people first as we push the boundaries of science, make healthcare more accessible, and treat, prevent and even cure diseases that affect millions of lives. Because it takes an unordinary approach to drive real, lasting change in health.

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

We’re not your typical healthcare company. In a modern world of quick fixes, we focus on solutions to defeat serious chronic diseases and promote long-term health. Our unordinary mindset is at the heart of everything we do. We seek out new ideas and put people first as we push the boundaries of science, make healthcare more accessible, and treat, prevent, and even cure diseases that affect millions of lives. Because it takes an unordinary approach to drive real, lasting change in health.





DETAILS TO REGISTER FOR THIS JOB:
NOTE: Apply to this job with an ATS-friendly CV!

https://careers.novonordisk.com/job/Prague-Clinical-Operations-Manager-Czec/1280613501/?source=Indeed



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